Brain 'Fingerprinting' Provides Insights Into Mental Health of Young Adolescents – Neuroscience News

Neuroscience research articles are provided.
What is neuroscience? Neuroscience is the scientific study of nervous systems. Neuroscience can involve research from many branches of science including those involving neurology, brain science, neurobiology, psychology, computer science, artificial intelligence, statistics, prosthetics, neuroimaging, engineering, medicine, physics, mathematics, pharmacology, electrophysiology, biology, robotics and technology.
– These articles focus mainly on neurology research.
– What is neurology?
– Definition of neurology: a science involved in the study of the nervous systems, especially of the diseases and disorders affecting them.
– Neurology research can include information involving brain research, neurological disorders, medicine, brain cancer, peripheral nervous systems, central nervous systems, nerve damage, brain tumors, seizures, neurosurgery, electrophysiology, BMI, brain injuries, paralysis and spinal cord treatments.
What is Psychology?
Definition of Psychology: Psychology is the study of behavior in an individual, or group. Our psychology articles cover research in mental health, psychiatry, depression, psychology, schizophrenia, autism spectrum, happiness, stress and more.
Artificial Intelligence articles involve programming, neural engineering, artificial neural networks, artificial life, a-life, floyds, boids, emergence, machine learning, neuralbots, neuralrobotics, computational neuroscience and more involving A.I. research.
Robotics articles will cover robotics research press releases. Robotics news from universities, labs, researchers, engineers, students, high schools, conventions, competitions and more are posted and welcome.
Genetics articles related to neuroscience research will be listed here.
Neurotechnology research articles deal with robotics, AI, deep learning, machine learning, Brain Computer Interfaces, neuroprosthetics, neural implants and more. Read the latest neurotech news articles below.
Summary: Neuroimaging of a person’s unique brain activity may help predict mental health problems during adolescence, a new study reports.
Source: University of the Sunshine Coast
Medical imaging of a person’s unique brain signature—much like a fingerprint—has the potential to predict mental health problems in young adolescents, according to a world-first study by University of the Sunshine Coast researchers.
In a study published in NeuroImage, researchers at USC’s Thompson Institute tested the uniqueness of individual adolescent brain activity patterns, and whether changes in their brain networks were associated with their mental health symptoms at different timepoints.
“We examined if there were unique patterns of neural activity in brain networks that might be associated with emerging troubling, confusing, and frustrating feelings experienced by adolescents, particularly those who may be vulnerable to mental health disorders,” said Dr. Shan, Head of Neuroimaging Platform at the Thompson Institute.
Dr. Shan, who was lead author of the study, said the team characterized the development of various brain “functional networks” in young adolescents from brain scans undertaken every four months on a group of about 70 participants, starting at the age of 12 through to 15 years.
Each time the scans were taken, the participants also completed questionnaires asking about their feelings over the past 30 days, particularly about their levels of depression and anxiety.
“The findings highlight the importance of longitudinal neuroimaging to monitor mental health in adolescents—at a time when the brain is growing and changing dramatically in both structure and function—and its potential to detect changes before abnormal behaviors present,” Dr. Shan said.
“Given the nature of emerging mental illness in young people, a continuous measure of psychological distress is more likely to reveal important links between neurobiological measures and mental illness.”
Mapping changes in the brain as they happen
The data was collected as part of the Longitudinal Adolescent Brain Study (LABS) by the Thompson Institute—a study designed to track changes in the brain during adolescence, and to gain a deeper understanding of the factors that impact adolescent mental health.
More than half of all mental health problems are established before the age of 14. In Australia, one in four young people aged 15 to 19 meet the criteria for having a probable serious mental illness.
The brain signature “uniqueness” was determined by how similar an individual was to themselves at other timepoints, as well as how similar they were to their peers (other participants).
Key insights into the differences and similarities of young minds
Like a fingerprint, each human brain has a unique profile of signals between different regions of the brain that becomes more individual and specialized as people age.
“The brain works like a symphony orchestra, with activities from different brain areas synchronizing in tune to determine our thoughts and behavior,” Dr. Shan said.
Unique whole brain synchronization was confirmed to exist in 12-year-olds, with 92 percent of participants having their own functional connectomes or unique brain “fingerprints.”
Further analysis of 13 individual brain networks discovered uniqueness in some networks by the age of 12, while others were still maturing and establishing.
Importantly, the brain network that controls individual “cognitive flexibility” and the ability to handle negative influences, known as the “cingulo-opercular network” (or CON) was found to have low uniqueness levels.
“This suggests that it hasn’t quite reached maturation yet and thus provides a biological explanation of the increased vulnerability in young people,” Dr. Shan said.
“Combined with the existence of a high level of whole-brain uniqueness, the results suggested that adolescents are capable of engaging these systems to regulate daily behavior. But they’re not yet doing so in a controlled, sustained, reliable fashion.”
A key finding was that CON uniqueness was significantly and negatively associated with subsequent levels of psychological distress when assessed four months later.
“This relationship reflected the importance of the CON in the mental health of adolescents. In future studies, we are planning to disentangle if this reflects a worsening of pre-existing experiences or whether a lag in forming a unique system triggers an increase in psychological distress,” Dr. Shan said.
The networks showing the highest uniqueness were the “frontoparietal network,” which is responsible for immediate information processing, and the “default mode network” which is important for internal cognitive processes, such as thinking about oneself or the future.
Author: Press Office
Source: University of the Sunshine Coast
Contact: Press Office – University of the Sunshine Coast
Image: The image is in the public domain
Original Research: Open access.
A longitudinal study of functional connectome uniqueness and its association with psychological distress in adolescence” by Zack Y Shan et al. NeuroImage
A longitudinal study of functional connectome uniqueness and its association with psychological distress in adolescence
Each human brain has a unique functional synchronisation pattern (functional connectome) analogous to a fingerprint that underpins brain functions and related behaviours.
Here we examine functional connectome (whole-brain and 13 networks) maturation by measuring its uniqueness in adolescents who underwent brain scans longitudinally from 12 years of age every four months.
The uniqueness of a functional connectome is defined as its ratio of self-similarity (from the same subject at a different time point) to the maximal similarity-to-others (from a given subject and any others at a different time point).
We found that the unique whole brain connectome exists in 12 years old adolescents, with 92% individuals having a whole brain uniqueness value greater than one.
The cingulo-opercular network (CON; a long-acting ‘brain control network’ configuring information processing) demonstrated marginal uniqueness in early adolescence with 56% of individuals showing uniqueness greater than one (i.e., more similar to her/his own CON four months later than those from any other subjects) and this increased longitudinally.
Notably, the low uniqueness of the CON correlates (β = -18.6, FDR-Q < < 0.001) with K10 levels at the subsequent time point. This association suggests that the individualisation of CON network is related to psychological distress levels.
Our findings highlight the potential of longitudinal neuroimaging to capture mental health problems in young people who are undergoing profound neuroplasticity and environment sensitivity period.
Your email address will not be published.

Neuroscience News Sitemap
Neuroscience Graduate and Undergraduate Programs
Free Neuroscience MOOCs
Neuroscience Groups
Contact Us
Privacy Policy
Submit Neuroscience News
Subscribe for Emails
Coronavirus News
Neuroscience Research
Psychology News
Brain Cancer Research
Alzheimer’s Disease
Parkinson’s News
Autism / ASD News
Neurotechnology News
Artificial Intelligence News
Robotics News


Leave a Reply

Your email address will not be published.